According to Destructoid, we could be expecting multiplayer modes in Uncharted: Golden Abyss and Resistance Burning Skies.
When asked about multiplayer, an Uncharted developer stated that we will see “something different” which may or may not mean a multiplayer mode, but it is quite promising.
As far as Resistance goes, the developer seemed adamant to recreate the console experience. This could also point towards multiplayer on the handheld platform.
We will only know for sure when the games finally launch on their respective dates.